DISOLCEL® Croscarmellose Sodium is an internally cross-linked Carboxymethylcellulose Sodium. Cross-linking was achieved without the use of cross-linking agents. Compared to the soluble Carboxymethylcellulose Sodium, cross-linked DISOLCEL® is essentially water-insoluble, yet swelling and absorbing many times its weight in water. As a result, it provides superior tablet disintegration and dissolution characteristics, thus assuring the bioavailability of the drug.
DISOLCEL® Croscarmellose Sodium solves many a formulator's problems with long-term functional stability, effects of high tablet hardness, and the need for high disintegrant use levels.
DISOLCEL® Croscarmellose Sodium is a pure, off-white, free-flowing powder, which does not interfere with binding or flow at typical use levels. DISOLCEL® Croscarmellose Sodium is the choice of excipient and superdisintegrant because of consistency in performance.